There have been many double-blind scientific studies showing a significant reduction in migraine severity, migraine attack frequency, and duration of migraine headaches in migraine sufferers. Please see references below.
- Alternative headache treatments: nutraceuticals, behavioral and physical treatments- PubMed- NCBI
- Role of magnesium in the pathogenesis and treatment of migraine- PubMed-NCBI
- Role of Magnesium, Coenzyme Q10, Riboflavin, and Vitamin B12 in Migraine Prophylaxis
- [Effectiveness of chemical, herbal and dietetic migraine prophylactics. An overview of randomized controlled double-blind studies]- PubMed- NCBI
- Pathophysiological basis of migraine prophylaxis
- Non-pharmacological management of migraine during pregnancy- PubMed- NCBI
- Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial- PubMed- NCBI
- Non-pharmacological approach to migraine prophylaxis: part II- PubMed- NCBI
- Relation between serum magnesium level and migraine attacks- PubMed- NCBI
- Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine- PubMed- NCBI
- Cephalalgia. 1996 Jun;16(4):257-63